In this chapter we will show how magnesium increases the efficiency of the white blood cells. For this we will turn to the celebrated work of Pierre Delbet, called Politique Préventif du Cancer.
There is, on the average, only one of these cells for each 150 of the red blood cells. These white corpuscles have a unique power. When the bloodstream is invaded by harmful bacteria or any other foreign matter, these white cells are somehow attracted to the source of the invasion, such as a wound, and go to work actually swallowing, and digesting the foreign matter and thus rendering it harmless. They do the same with any foreign bodies that infiltrate the bloodstream. They are the body's first and most important defense against all types of infection.
But to increase the number of such cells circulating in the bloodstream would be a very dangerous thing. Leukemia, cancer of the blood, is marked by precisely such an increase. The destructive capacity of these cells is so great that their numbers must be kept at normal proportions for fear of the damage they might do our own systems if they got out of hand.
But on the other hand, think what it could mean if we could induce the white cells in our blood to double their protective activity without any increase in numbers. It would reduce sharply the possibility that invaders of the bloodstream could get by these defenders and do consequent damage to our systems. It would mean that the need for drugs to fight bacterial invasions would be just about eliminated. It would mean bringing the protective ability of everybody's blood up to the level that is now possessed by the superbly healthy individual.
And that is just what Pierre Delbet claims that magnesium can do for us. He describes this in a paper he submitted in collaboration with Dr. Karalanopoulo to the French Academy of Science, September 6, 1915, titled Cytophylaxis, which means work done by the white cells or phagocytes in destroying invaders of the bloodstream.
The paper summarized a study Delbet made of the effect on body cells of various known solutions Used to dress wounds, in order to find a better solution. He mixed in test tubes white corpuscles, microbes, and the solution to be tested, then studied the destruction of foreign bodies by the white cells after a lapse of 20 minutes. He used 16,000 white blood cells and 19,716 microbes.
Of the solutions studied, potassium permanganate and Labarraque's solution destroyed the red and white corpuscles to such an extent that it was impossible to recognize anything in the preparations. A similar effect was noted with Formalin.
Other solutions were less destructive. These included hydrogen peroxide, phenolic acid, Gram's solution, and cyanide of mercury. Sodium chloride was somewhat better.
Tests showed that, as antiseptics, these solutions were inadequate. The problem was to kill the microbes without killing the blood cells.
Since table salt (sodium chloride) showed up best in all these tests, various solutions of this type were tested but did not compare with the effectiveness of magnesium chloride. Delbet says, "A solution of magnesium chloride at 12.1 parts per 1,000 gave extraordinary results. It increased the proportion of phagocytosis [killing microbes] by 75 per cent as compared with the solution of sodium chloride at 8 parts per 1,000 which itself gave 63 per cent more than the Locke-Ringer's solution. The increase is based on the number of polynucleates [white cells] as well as the phagocytic [germ-destroying] power of each of them.
"These experiments prove that a solution of desiccated chloride of magnesium at 12.1 parts per 1,000 has a special effect on the white corpuscles, which is not the case with either physiological serum [a solution of chloride of sodium at seven parts per 1,000] or seawater, or the solution of Locke-Ringer which was considered best for maintaining the activity of cells.
"Consequently, a solution of chloride of magnesium was better than all the solutions previously used in the washing and dressing of wounds."
In another communication to the French Academy of Medicine (September 7, 1915), Dr. Delbet describes researches that proved the effectiveness of magnesium within the body. He injected 150 cc. of a solution of magnesium chloride into the vein of a dog, taking a blood sample before the injection and a second one 35 minutes afterward. Then the white corpuscles were presented with microbes from the same culture to see their effect on or power to destroy them.
Five hundred white cells in the first sample destroyed 245 microbes. Five hundred white cells from the second destroyed 681. This increase in microbe-killing under the influence of magnesium chloride was 180 percent over the other solutions.
More experiments were performed; in one there was an increase to 129 percent, in another, 333 percent.
Thus not only is the action of chloride of magnesium effective outside of the body but also inside. And the magnesium solution is not toxic.
Delbet says,
"Used in dressings and in subcutaneous injections, the solution of chloride of magnesium, in my opinion, seemed to be effective. I think it enabled me to avoid amputating the thigh of a soldier which I decided to amputate for an arthritis of the knee with the crushing of the knee-cap and of the external condyle of the femur.
"These experiments have enlarged to a remarkable extent the role of cytophylaxis. From a mere technique in dressing wounds it has become a general method which not only increases the resistance of the body against infection, but also against vitamin deficiency, against anaphylaxis, senile decay and cancer.
"I first used chloride of magnesium alone. At the beginning of 1928, after becoming acquainted with the famous works of Grignard on the synthetic power of the organo-magnesic compounds, I added to chloride small quantities of other halogenous salts of this metal. After some tentative efforts, I arrived in collaboration with Dr. Chapelle at the formula which I have described on page 15. [of this book]. It has been named 'delbiase.' Since March, 1928, all my experimental and clinical researches have been carried out with delbiase."
Regarding what Delbet means by delbiase, the following is a quote from his book above mentioned:
"The fine work of Grignard on the possibility of synthesizing organic compounds of magnesium led me to add to magnesium chloride small quantities of other halogenated salts of this metal: bromide, iodide, fluoride. I made compounds of which the formula is the following:
Magnesium chloride |
0.592 |
Magnesium bromide |
0.020 |
Magnesium iodide |
0.0001 |
Magnesium fluoride |
0.0009 |
"In the anhydrous alts, those supposedly desiccated by crystallization, this is the result:
Magnesium chloride anhydrous |
0.379 |
Magnesium bromide |
0.013 |
Magnesium iodide |
0.000072 |
Magnesium fluoride |
0.00009 |
"These compounds are named delbiase."
This page was first uploaded to The Magnesium Web Site on January 3, 2001
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